Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

Search Within Results

2,086 – 2,100 of 6,680 results

2,086

Medchemexpress LLC Iptacopan (hydrochloride) | 1646321-63-2 | 99.83% | 25 MG

Iptacopan (LNP023) hydrochloride is an effective, orally-active, and highly selective factor B inhibitor. With an IC50 of 10 nM and a KD of 7.9 nM, it exerts a proximal effect in the complement cascade reaction, preventing the destruction of red blood cells in PNH and damage to renal cells in IgAN and C3G. It is used for studying complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G).

Highly selective factor B inhibitor.
Orally active.
Potent inhibition of alternative complement pathway (AP)-induced membrane attack complex (MAC) formation.
Excellent selectivity over other proteases.
Prevents destruction of red blood cells in PNH.
Prevents damage to renal cells in IgAN and C3G.
Used for studying complement-mediated diseases.

Pricing & Availability

2,087

Medchemexpress LLC SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 1 ML

SCH-23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. It is also a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM, and binds with high affinity to 5-HT2 and 5-HT1C receptors. It inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM. For research use only.

Potent and selective dopamine D1-like receptor antagonist.
Potent and high efficacy human 5-HT2C receptor agonist.
Binds with high affinity to 5-HT2 and 5-HT1C receptors.
Inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels.
Used in studies of neurological disorders like psychosis and Parkinson's disease.
Used in topographical determination of brain D1 receptors.

Pricing & Availability

2,088

Medchemexpress LLC Reserpine (hydrochloride) | 16994-56-2 | 645.14 | 1 ML

Reserpine (hydrochloride) | 16994-56-2 | 645.14 | 1 ML

Pricing & Availability

2,089

Medchemexpress LLC EPZ004777 hydrochloride | 1380316-03-9 | C28H42ClN7O4 | 50 MG

EPZ004777 hydrochloride is an effective and selective DOT1L inhibitor, reducing H3K79me2 and H3K79me1 levels and down-regulating HOXA9 and MEIS1 expression. This compound selectively inhibits the proliferation of MLL rearrangement cells, promoting their differentiation and apoptosis, making it useful for leukemia research.

Target: histone methyltransferase; apoptosis
Pathway: epigenetics; apoptosis
Potent and selective DOT1L inhibitor (IC50 of 0.4 nM)
Reduces H3K79me2 and H3K79me1 levels, down-regulating HOXA9 and MEIS1 expression
Selectively inhibits MLL rearrangement cells, promoting differentiation and apoptosis
Well tolerated in vivo with no overt toxicity observed

Pricing & Availability

2,090

Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.9% | 50 MG

Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM, showing high selectivity for AChE over BuChE. It exhibits a neuroprotective effect on Aβ42 neurotoxicity. In vivo, Donepezil treatment prevents the progression of scopolamine-induced memory impairment in mice, demonstrating its potential in neurodegenerative research.

Reversible, selective AChE inhibitor
IC50 of 6.7 nM for AChE activity
High selectivity for AChE over BuChE
Exhibits a neuroprotective effect on Aβ42 neurotoxicity
Enhances phosphorylation of Akt and GSK-3β
Reduces phosphorylation of tau and glycogen synthase
Increases cell viability in cortical neuronal cells
Prevents scopolamine-induced memory impairment in mice

Pricing & Availability

2,091

eMolecules 51285-26-8 | Picolinimidamide hydrochloride | Ambeed | MFCD00052271 | 157.600 | C6H8ClN3 | 97.000 | Cl.NC(=N)c1ccccn1 | 10g | 490512023

Picolinimidamide hydrochloride | Ambeed | 51285-26-8 | MFCD00052271 | 157.600 | C6H8ClN3 | 97.000 | Cl.NC(=N)c1ccccn1 | 10g | 490512023

Pricing & Availability

2,092

Medchemexpress LLC Pnu 37883 hydrochloride | 57568-80-6

Pnu 37883 hydrochloride | 57568-80-6

Pricing & Availability

2,093

Medchemexpress LLC Amrubicin hydrochloride | 110311-30-3 | 98.78% | C25H26ClNO9 | 5 MG

Amrubicin hydrochloride (SM-5887) is a DNA topoisomerase II inhibitor used for cancer research. It exhibits radio-enhancement effects on human lung adenocarcinoma A549 cells and suppresses various other cell lines. It also induces apoptosis in U937 cells and demonstrates significant antitumor activities against SCLC tumors in vivo.

DNA topoisomerase II inhibitor.
Used for research of cancer.
Exhibits radio-enhancement effects on human lung adenocarcinoma A549 cells.
Suppresses LX-1, A549, A431, and BT-474 cell lines.
Induces apoptosis in U937 cells and activates caspase-3/7.
Reduces mitochondrial membrane potential (Δψm).
Demonstrates significant antitumor activities against SCLC tumors.
In combination with cisplatin and irinotecan, it significantly inhibits tumor growth.
Suppresses tumor growth in human cancer xenograft models.

Pricing & Availability

2,094

eMolecules 29671-92-9 | Chloroformamidine hydrochloride | Ochem Incorporation | MFCD00035527 | 114.960 | CH4Cl2N2 | 98.000 | Cl.NC(Cl)=N | 1g | 773154938

Chloroformamidine hydrochloride | Ochem Incorporation | 29671-92-9 | MFCD00035527 | 114.960 | CH4Cl2N2 | 98.000 | Cl.NC(Cl)=N | 1g | 773154938

Pricing & Availability

2,095

eMolecules 51285-26-8 | 2-Amidinopyridine Hydrochloride | Accela ChemBio (ASD) | MFCD00052271 | 157.600 | C6H8ClN3 | 95.000 | Cl.NC(=N)c1ccccn1 | 5g | 485582374

2-Amidinopyridine Hydrochloride | Accela ChemBio (ASD) | 51285-26-8 | MFCD00052271 | 157.600 | C6H8ClN3 | 95.000 | Cl.NC(=N)c1ccccn1 | 5g | 485582374

Pricing & Availability

2,096

Medchemexpress LLC Ru-ski 43 hydrochloride | 1782573-67-4 | 98.8% | 423.01 | 50 MG

RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. It also exhibits anti-cancer activity.

Potent and selective Hhat inhibitor (IC50 = 850 nM).
Reduces Gli-1 activation via Smoothened-independent non-canonical signaling.
Decreases Akt and mTOR pathway activity.
Possesses anti-cancer activity.

Pricing & Availability

2,097

Medchemexpress LLC Benzamide, N-(3-aminopropyl)-N-[(1R)-1-[7-chloro-4-oxo-3-(phenylmethyl)-4H-1-benzopyran-2-yl]-2-methylpropyl]-4-methyl-, hydrochloride | 940929-33-9 | 99.8% | 553.52 | 25 MG

Benzamide, N-(3-aminopropyl)-N-[(1R)-1-[7-chloro-4-oxo-3-(phenylmethyl)-4H-1-benzopyran-2-yl]-2-methylpropyl]-4-methyl-, hydrochloride | 940929-33-9 | 99.8% | 553.52 | 25 MG

Pricing & Availability

2,098

Medchemexpress LLC BMS-199264 hydrochloride | 186180-83-6 | 99.3% | 567.53 g/mol | C26H32Cl2N4O4S | 25 MG

BMS-199264 hydrochloride is a research-grade small-molecule inhibitor of the F1F0 ATP hydrolase provided as a high-purity solid for biochemical and cardiac ischemia/reperfusion studies in vitro and in vivo.

High purity (99.28%).
Molecular weight 567.53 g/mol.
Chemical formula C26H32Cl2N4O4S.
Supplied as a 25 MG package.
Appearance: solid; storage: 4°C; in solution store at -80°C (6 months) or -20°C (1 month).

Pricing & Availability

2,099

Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 50 MG

Dopexamine hydrochloride is a β2 adrenergic receptor agonist and dopamine analogue. It acts on β2 and dopaminergic receptors to attenuate systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury. This compound helps reduce inflammation, cytokine release, endothelial adhesion molecules, and oxidative stress without significantly altering blood pressure or stroke volume.

Attenuates systemic inflammatory response
Reduces tissue leukocyte infiltration
Protects against organ injury
Reduces systemic inflammatory response to endotoxin
Reduces cytokine release
Reduces endothelial adhesion molecules
Reduces oxidative stress
Does not substantially change systemic hemodynamics

Pricing & Availability

2,100

Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 1 G

Octodrine (2-Amino-6-methylheptane) is identified as a central nervous activator. It functions by increasing the uptake of dopamine and noradrenaline. Studies have indicated that Octodrine can increase the pain threshold, cardiac rate (exhibiting a positive chronotropic effect), and myocardial contractility (showing a positive inotropic effect). This product is intended for research use only and is not sold to patients.

Increases uptake of dopamine and noradrenaline.
Increases pain threshold.
Increases cardiac rate (positive chronotropic effect).
Increases myocardial contractility (positive inotropic effect).
For research use only.
Store at 4°C, sealed, away from moisture.

Pricing & Availability

Alcohols and polyols

Filtered Search Results

Narrow Results

Medchemexpress LLC Iptacopan (hydrochloride) | 1646321-63-2 | 99.83% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Reserpine (hydrochloride) | 16994-56-2 | 645.14 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EPZ004777 hydrochloride | 1380316-03-9 | C28H42ClN7O4 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.9% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pnu 37883 hydrochloride | 57568-80-6 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amrubicin hydrochloride | 110311-30-3 | 98.78% | C25H26ClNO9 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ru-ski 43 hydrochloride | 1782573-67-4 | 98.8% | 423.01 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BMS-199264 hydrochloride | 186180-83-6 | 99.3% | 567.53 g/mol | C26H32Cl2N4O4S | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More